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For many years, it was not at all clear why animals required such complex control

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Because research is limited, side-effect information is not as strong as it is for FDA-approved medications

Birendra KC, Kantarjian HM, Garcia-Manero G, Daver N, Borthakur G , Konopleva M, Andreeff M, Chihara D, Kadia T, Bose P, Estrov Z, Pemmaraju N, Ravandi F, Cortes JE